Английская Википедия:Gonadotropin-releasing hormone family

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Версия от 21:02, 15 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Family of peptides important in reproduction}} {{multiple issues|{{more footnotes|date=November 2010}} {{one source|date=November 2010}}}} {{Pfam_box | Symbol = GnRH | Name = Gonadotropin-releasing hormone | image = | width = | caption = | Pfam= PF00446 | InterPro= IPR002012 | SMART= | Prosite = PDOC00432 | SCOP = | TCDB = | OPM family= | OPM protein=...»)
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Шаблон:Short description Шаблон:Multiple issues Шаблон:Pfam box

The gonadotropin-releasing hormones (GnRH) (gonadoliberin)[1] are a family of peptides that play a pivotal role in reproduction. The main function of GnRH is to act on the pituitary to stimulate the synthesis and secretion of luteinizing and follicle-stimulating hormones, but GnRH also acts on the brain, retina, sympathetic nervous system, gonads, and placenta in certain species. There seems to be at least three forms of GnRH. The second form is expressed in midbrain and seems to be widespread. The third form has been found so far only in fish. GnRH is a C-terminal amidated decapeptide processed from a larger precursor protein. Four of the ten residues are perfectly conserved in all species where GnRH has been sequenced.

Subfamilies

Human proteins containing this domain

GNRH1, GNRH2

References

Шаблон:Reflist

Шаблон:InterPro content