Просмотр кода страницы Английская Википедия:Excitatory amino acid transporter 5

{{Английская Википедия/Панель перехода}}
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{{Short description|Protein found in humans}}
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'''Excitatory amino-acid transporter 5''' (EAAT5) is a [[protein]] that in humans is encoded by the ''SLC1A7'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: solute carrier family 1 (glutamate transporter)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6512}}</ref><ref name="pmid9108121">{{cite journal | vauthors = Arriza JL, Eliasof S, Kavanaugh MP, Amara SG | title = Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 94 | issue = 8 | pages = 4155–60 |date=April 1997 | pmid = 9108121 | pmc = 20584 | doi = 10.1073/pnas.94.8.4155| bibcode = 1997PNAS...94.4155A | doi-access = free }}</ref>

EAAT5 is expressed predominantly in the [[retina]], has high affinity for the [[excitatory amino acid]] L-[[glutamic acid|glutamate]].  When stimulated by this amino acid, EAAT5 conducts chloride ions.<ref name="pmid9108121 "/>

==References==
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==Further reading==
{{refbegin | 2}}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
*{{cite journal  |vauthors=Wistow G, Bernstein SL, Ray S |title=Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium. |journal=Mol. Vis. |volume=8 |pages= 185–95 |year= 2002 |pmid= 12107412 |display-authors=etal}}
*{{cite journal  |vauthors=Boehmer C, Rajamanickam J, Schniepp R |title=Regulation of the excitatory amino acid transporter EAAT5 by the serum and glucocorticoid dependent kinases SGK1 and SGK3. |journal=Biochem. Biophys. Res. Commun. |volume=329 |issue= 2 |pages= 738–42 |year= 2005 |pmid= 15737648 |doi= 10.1016/j.bbrc.2005.02.035 |display-authors=etal}}
*{{cite journal  |vauthors=Gratacòs M, Costas J, de Cid R |title=Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. |journal=Am. J. Med. Genet. B Neuropsychiatr. Genet. |volume=150B |issue= 6 |pages= 808–16 |year= 2009 |pmid= 19086053 |doi= 10.1002/ajmg.b.30902 |s2cid=44524739 |display-authors=etal|doi-access= }}
*{{cite journal  |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
{{refend}}

{{Membrane transport proteins|bg|bg0}}
{{Glutamate metabolism and transport modulators}}

[[Category:Solute carrier family]]
[[Category:Glutamate (neurotransmitter)]]


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