Английская Википедия:2-oxoisovalerate dehydrogenase (acylating)
Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 2-oxoisovalerate dehydrogenase (acylating) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction
- 3-methyl-2-oxobutanoate + CoA + NAD+ <math>\rightleftharpoons</math> 2-methylpropanoyl-CoA + CO2 + NADH
The 3 substrates of this enzyme are 3-methyl-2-oxobutanoate, CoA, and NAD+, whereas its 3 products are 2-methylpropanoyl-CoA, CO2, and NADH.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating). Other names in common use include 2-oxoisovalerate dehydrogenase, and alpha-ketoisovalerate dehydrogenase. This enzyme participates in valine, leucine and isoleucine degradation.
References
Шаблон:Aldehyde/Oxo oxidoreductases Шаблон:Enzymes Шаблон:Portal bar