Английская Википедия:A-86929

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A-86929 is a synthetic compound that acts as a selective dopamine receptor D1 agonist.[1][2] It was developed as a possible treatment for Parkinson's disease,[3] as well as for other applications such as treatment of cocaine addiction,[4][5] but while it had reasonable efficacy in humans it also caused dyskinesias and has not been continued.[6][7] It has mainly been used as its diacetate ester prodrug adrogolide (ABT-431), which has better bioavailability.[8][9]

Файл:Adrogolide.svg
Adrogolide

References

Шаблон:Reflist

Шаблон:Dopamine receptor modulators


Шаблон:Nervous-system-drug-stub