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...}}</ref> and has 100-fold lower [[affinity (pharmacology)|affinity]] for [[GPER]] (GPR30) relative to [[estradiol]].<ref name="pmid20138435">{{cite journal [[Category:GPER agonists]] ...

...It is also an [[agonist]] of the [[G protein-coupled estrogen receptor]] (GPER) with relatively low [[affinity (pharmacology)|affinity]] (100–1,000&nbsp [[Category:GPER agonists]] ...

...t1=E.R. |last2=Barton|first2=M. |title=Estrogen biology: New insights into GPER function and clinical opportunities|journal=Molecular and Cellular Endocrin [[Category:GPER agonists]] ...

...rotein-Coupled Receptor 30 (GPR30) or G-Protein-Coupled Estrogen Receptor (GPER) | series = Methods in Molecular Biology | volume = 1366 | pages = 11–7 | [[Category:GPER agonists]] ...

...| date = Jan 1998 | pmid = 9479505 | doi = 10.1006/geno.1998.5095 }}</ref> GPER binds to and is activated by the female sex hormone [[estradiol]] and is re ...stradiol, GPR30 was renamed as G protein-coupled estrogen receptor (GPER). GPER is localized in the plasma membrane but is predominantly detected in the [[ ...

...or antagonist|antagonist]] of the [[G protein-coupled estrogen receptor]] (GPER) (100–1,000&nbsp;μM).<ref name="pmid26023144">{{cite journal | vauthors ...rotein-Coupled Receptor 30 (GPR30) or G-Protein-Coupled Estrogen Receptor (GPER)|volume=1366|year=2016|pages=11–17|issn=1064-3745|doi=10.1007/978-1-4939- ...

...g [[Gonadotropin-releasing hormone|luteinizing hormone releasing hormone]] agonists, such as [[Goserelin|goserilin]]). In postmenopausal women, the ovaries cea ...ER modulators]] (SERMs), like [[tamoxifen]]. SERMs act as partial estrogen agonists, competing with estrogen to bind ER. ...

...|last2=Barton |first2=Matthias |title=Estrogen biology: New insights into GPER function and clinical opportunities |journal=Molecular and Cellular Endocri [[Category:GPER agonists]] ...

...uthors = Barton M | title = Position paper: The membrane estrogen receptor GPER--Clues and questions | journal = Steroids | volume = 77 | issue = 10 | page [[Category:GPER agonists]] ...

...R.|last2=Barton|first2=Matthias|title=Estrogen biology: New insights into GPER function and clinical opportunities|journal=Molecular and Cellular Endocrin [[Category:GPER agonists]] ...

[[Category:GPER agonists]] ...

...elative to the normal ERα.<ref name="pmid27754803" /> A group of other ERα agonists that included [[ethinylestradiol]], [[diethylstilbestrol]], [[tamoxifen]], ...ia signaling through the [[ERβ]] and [[G protein-coupled estrogen receptor|GPER]] (i.e., that not all of the observed phenotypes may have simply been due t ...

...[[intracellular]] receptors, and [[membrane estrogen receptor]]s (mERs) ([[GPER]] (GPR30), [[ER-X]], and [[Gq-mER|G_q-mER]]), which are mostly [[ ===Agonists=== ...

...|last2=Barton |first2=Matthias |title=Estrogen biology: New insights into GPER function and clinical opportunities |journal=Molecular and Cellular Endocri ...a M. |last16=Atanasov |first16=Atanas G. |year=2014 |title=Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): A review |jou ...

...eceptor]]s ([[ERα]], [[ERβ]], [[Membrane estrogen receptor|mER]]s (e.g., [[GPER]], others)) ...rmonal agent used in the treatment of endometriosis. In the 1990s the GnRH agonists have become the most frequently used drugs for the treatment of endometrios ...

...|last2=Barton |first2=Matthias |title=Estrogen biology: New insights into GPER function and clinical opportunities |journal=[[Molecular and Cellular Endoc [[Category:GPER agonists]] ...

...1847610 | doi = 10.1016/j.mce.2006.12.010 }}</ref> Additional mERs besides GPER include [[ER-X]], [[ERx]], and [[Gq-mER|G_q-mER]].<ref name="pmid [[Category:GPER agonists]] ...

[[Category:GPER agonists]] ...

...ors = Prossnitz ER, Barton M | title = Estrogen biology: new insights into GPER function and clinical opportunities | journal = Molecular and Cellular Endo [[Category:GPER agonists]] ...

...estradiol in established disease was demonstrated to require expression of GPER but not ERα, and was associated with the production of the anti-inflammato [[Category:GPER agonists]] ...