Английская Википедия:(S)-2-hydroxy-acid oxidase
Шаблон:Short description Шаблон:Infobox enzyme In enzymology, an (S)-2-hydroxy-acid oxidase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction
- (S)-2-hydroxy acid + OШаблон:Sub <math>\rightleftharpoons</math> 2-oxo acid + HШаблон:SubOШаблон:Sub
Thus, the two substrates of this enzyme are (S)-2-hydroxy acid and [[oxygen|OШаблон:Sub]], whereas its two products are 2-oxo acid and [[hydrogen peroxide|HШаблон:SubOШаблон:Sub]].
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is (S)-2-hydroxy-acid:oxygen 2-oxidoreductase. Other names in common use include glycolate oxidase, hydroxy-acid oxidase A, hydroxy-acid oxidase B, oxidase, L-2-hydroxy acid, hydroxyacid oxidase A, L-alpha-hydroxy acid oxidase, and L-2-hydroxy acid oxidase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, FMN.
Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.
References
- Шаблон:Cite journal
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- Шаблон:Cite journal
- Шаблон:Cite journal
- Шаблон:Cite journal
- Шаблон:Cite journal
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Шаблон:Alcohol oxidoreductases Шаблон:Enzymes Шаблон:Portal bar
