Английская Википедия:2-alkenal reductase

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Версия от 13:55, 21 декабря 2023; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Class of enzymes}} {{infobox enzyme | Name = 2-alkenal reductase | EC_number = 1.3.1.74 | CAS_number = 9032-20-6 | GO_code = 0032440 | image = 1zsv.jpg | width = 270 | caption = Leukotriene B4 12-hydroxydehydrogenase (NADP-dependent) dimer, Human }} In enzymology, a '''2-alkenal reductase''' ({{EC number|1.3.1.74}}) is an enzyme that [...»)
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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 2-alkenal reductase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

n-alkanal + NAD(P)+ <math>\rightleftharpoons</math> alk-2-enal + NAD(P)H + H+

The 3 substrates of this enzyme are n-alkanal, NAD+, and NADP+, whereas its 4 products are alk-2-enal, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is n-alkanal:NAD(P)+ 2-oxidoreductase. Other names in common use include NAD(P)H-dependent alkenal/one oxidoreductase, and NADPH:2-alkenal alpha,beta-hydrogenase.

Structural studies

As of late 2007, three structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:CH-CH oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.3-enzyme-stub