Английская Википедия:2-aminoethylphosphonate—pyruvate transaminase
Шаблон:Short description Шаблон:Infobox enzyme
In enzymology, a 2-aminoethylphosphonate—pyruvate transaminase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction
- (2-aminoethyl)phosphonate + pyruvate <math>\rightleftharpoons</math> 2-phosphonoacetaldehyde + L-alanine
Thus, the two substrates of this enzyme are (2-aminoethyl)phosphonate and pyruvate, whereas its two products are 2-phosphonoacetaldehyde and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is (2-aminoethyl)phosphonate:pyruvate aminotransferase. Other names in common use include (2-aminoethyl)phosphonate transaminase, (2-aminoethyl)phosphonate aminotransferase, (2-aminoethyl)phosphonic acid aminotransferase, 2-aminoethylphosphonate-pyruvate aminotransferase, 2-aminoethylphosphonate aminotransferase, 2-aminoethylphosphonate transaminase, AEP transaminase, and AEPT. This enzyme participates in aminophosphonate metabolism. It employs one cofactor, pyridoxal phosphate.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Шаблон:PDB link.
References
Шаблон:Nitrogenous transferases Шаблон:Enzymes Шаблон:Portal bar
