Английская Википедия:2-oxoisovalerate dehydrogenase (acylating)

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Версия от 14:02, 21 декабря 2023; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Class of enzymes}} {{infobox enzyme | Name = 2-oxoisovalerate dehydrogenase (acylating) | EC_number = 1.2.1.25 | CAS_number = 37211-61-3 | GO_code = 0047101 | image = | width = | caption = }} In enzymology, a '''2-oxoisovalerate dehydrogenase (acylating)''' ({{EC number|1.2.1.25}}) is an enzyme that catalyzes the che...»)
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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, a 2-oxoisovalerate dehydrogenase (acylating) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

3-methyl-2-oxobutanoate + CoA + NAD+ <math>\rightleftharpoons</math> 2-methylpropanoyl-CoA + CO2 + NADH

The 3 substrates of this enzyme are 3-methyl-2-oxobutanoate, CoA, and NAD+, whereas its 3 products are 2-methylpropanoyl-CoA, CO2, and NADH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating). Other names in common use include 2-oxoisovalerate dehydrogenase, and alpha-ketoisovalerate dehydrogenase. This enzyme participates in valine, leucine and isoleucine degradation.

References

Шаблон:Reflist

Шаблон:Aldehyde/Oxo oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.2-enzyme-stub

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