Английская Википедия:3,3-Dimethyl-1-butanol
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3,3-Dimethyl-1-butanol (DMB) is a structural analog of choline.[1]
Effects
DMB inhibits microbial trimethylamine (TMA) formation in mice and in human feces, thereby reducing plasma trimethylamine N-oxide (TMAO) levels after choline or carnitine supplementation.[1] It consequently inhibited choline-enhanced endogenous macrophage foam cell formation and atherosclerotic lesion development in mice without alterations in circulating cholesterol levels.[1]
While mice placed on a choline supplemented diet showed an increase in the proportions of the bacterial taxon Clostridiales in the gut, DMB induced a decrease in the proportions of this taxon.[1]
Mice showed no evidence of toxicity to chronic (16-week) DMB exposure.[1][2]
Occurrence
DMB is found in some balsamic vinegars, red wines, and some cold-pressed extra virgin olive oils and rapeseed oils.[1]
References
