Английская Википедия:3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)

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Версия от 02:28, 26 декабря 2023; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Enzyme}} {{DISPLAYTITLE:3alpha(17beta)-hydroxysteroid dehydrogenase (NAD<sup>+</sup>)}} {{infobox enzyme | Name = 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD<sup>+</sup>) | EC_number = 1.1.1.239 | CAS_number = 126469-82-7 | GO_code = 0047035 | image = | width = | caption = }} In enzymology, a '''3alpha(17beta)-hydroxysteroid dehy...»)
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Шаблон:Short description

Шаблон:Infobox enzyme In enzymology, a 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction:

testosterone + NAD+ <math>\rightleftharpoons</math> androst-4-ene-3,17-dione + NADH + H+

Thus, the two substrates of this enzyme are testosterone and NAD+, whereas its 3 products are androst-4-ene-3,17-dione, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase. Other names in common use include 3alpha,17beta-hydroxy steroid dehydrogenase, 3alpha(17beta)-HSD, and 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+). This enzyme participates in androgen and estrogen metabolism.

References

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Шаблон:Alcohol oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.1.1-enzyme-stub