Английская Википедия:5,10-Methenyltetrahydrofolate

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Версия от 06:47, 26 декабря 2023; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477223671 | ImageFile=5,10-Methenyltetrahydrofolate.svg | ImageSize=260 | ImageAlt = Skeletal formula of 5,10-methenyltetrahydrofolate | ImageFile1 = 5,10-Methenyltetrahydrofolate-cation-3D-spacefill.png | ImageSize1 = 250 | ImageAlt1 = Space-filling model of the 5,10-methenyltetrahydrofolate cation | IUPA...»)
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Шаблон:Chembox 5,10-Methenyltetrahydrofolate (5,10-CH=THF) is a form of tetrahydrofolate that is an intermediate in metabolism. 5,10-CH=THF is a coenzyme that accepts and donates methenyl (CH=) groups.

It is produced from 5,10-methylenetetrahydrofolate by either a NAD+ dependent methylenetetrahydrofolate dehydrogenase, or a NADP+ dependent dehydrogenase.[1] It can also be produced as an intermediate in histidine catabolism, by formiminotransferase cyclodeaminase, from 5-formiminotetrahydrofolate.

5,10-CH=THF is a substrate for methenyltetrahydrofolate cyclohydrolase, which converts it into 10-formyltetrahydrofolate.

Interactive pathway map

Шаблон:FluoropyrimidineActivity WP1601

References

Шаблон:Reflist

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  1. ↑ Шаблон:Cite journal
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