Английская Википедия:5-Aza-7-deazapurine

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Версия от 06:51, 26 декабря 2023; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{chembox | Watchedfields = changed | verifiedrevid = | ImageFile_Ref = {{chemboximage|correct|??}} | ImageFile = 5-aza-7-deazapurine.svg | ImageSize = 150 | PIN= Imidazo[1,2-''a''][1,3,5]triazine | OtherNames= 5-Aza-7-deazapurine |Section1={{Chembox Identifiers | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = | InChI = 1S/C5H4N4/c1-2-9-4-6-3-8-5(9)7-1/h1-4H | InChIKey = OXISDMSERFAPR...»)
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5-Aza-7-deazapurine or imidazo[1,2-a][1,3,5]triazine[1] is a heterocyclic aromatic organic compound that consists of a s-triazine ring fused to an imidazole ring. It is an isostere and isomer of purine. However, in 5-aza-7-deazapurine, N-9 of five-membered ring does not bond with hydrogen. So 5-aza-7-deazapurine derivatives must have an exocyclic substituent with a double bond to bind a sugar residue.[2] 5-Aza-7-deazapurine nucleosides may have an oxo, thioxo, or a imine group.

Notable derivatives of this molecule include 5-aza-7-deazaguanine,[2] which is a nucleobase of hachimoji DNA.

See also

References

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