Английская Википедия:ACSL3

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Версия от 23:54, 26 декабря 2023; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} '''Long-chain-fatty-acid—CoA ligase 3''' is an enzyme that in humans is encoded by the ''ACSL3'' gene.<ref name="entrez">{{cite web | title = Entrez Gene: ACSL3 acyl-CoA synthetase long-chain family member 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&Ter...»)
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Шаблон:Short description Шаблон:Infobox gene Long-chain-fatty-acid—CoA ligase 3 is an enzyme that in humans is encoded by the ACSL3 gene.[1]

Function

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.[1]

References

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External links

Further reading

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Шаблон:Gene-2-stub

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  1. ↑ 1,0 1,1 Шаблон:Cite web
Источник — http://wikihandbk.com/ruwiki/index.php?title=Английская_Википедия:ACSL3&oldid=12878815