Английская Википедия:ACV synthetase
Материал из Онлайн справочника
Шаблон:Short description Шаблон:Infobox enzyme ACV synthetase (ACVS, L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase, N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, Шаблон:EC number) is an enzyme that catalyzes the chemical reaction
- 3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O <math>\rightleftharpoons</math> 3 AMP + 3 PPi + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine
The five substrates of this enzyme are ATP, L-2-aminohexanedioate, L-cysteine, L-valine, and H2O, whereas its three products are AMP, diphosphate, and N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine.
ACVS is an example of a nonribosomal peptide synthetase (NRPS). It participates in penicillin and cephalosporin biosyntheses.
References
Шаблон:Ligases CO CS and CN Шаблон:Enzymes Шаблон:Portal bar
