Английская Википедия:ADB-BINACA
Шаблон:Short description Шаблон:Infobox drug
ADB-BINACA is a cannabinoid designer drug that has been found as an ingredient in some synthetic cannabis products.[1] It was originally developed by Pfizer as a potential analgesic, and is a potent agonist of the CB1 receptor with a binding affinity (Ki) of 0.33 nM and an EC50 of 14.7 nM.[2]
ADB-BUTINACA
The analogue with a 1-butyl substitution on the indazole ring rather than 1-benzyl has also been sold as a designer drug under the name ADB-BINACA, but is now more commonly referred to as ADB-BUTINACA to avoid confusion with the benzyl compound.[3][4][5][6][7] It is a similarly potent CB1 agonist, with a binding affinity of 0.29nM for CB1 and 0.91nM for CB2, and an EC50 of 6.36 nM for CB1.[8][9][10]
See also
- 4F-ADB
- 5F-AB-PINACA
- 5F-ADB
- 5F-ADB-PINACA
- ADB-CHMINACA
- ADB-FUBICA
- ADB-FUBINACA
- ADB-HEXINACA
- ADB-PINACA
- ADB-4en-PINACA
References
