Английская Википедия:Acute tryptophan depletion
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Acute tryptophan depletion (ATD) is a technique used extensively to study the effect of low serotonin in the brain.[1] This experimental approach reduces the availability of tryptophan, an amino acid which serves as the precursor to serotonin.[1][2] The lack of mood-lowering effects after ATD in healthy subjects seems to contradict a direct causal relationship between acutely decreased serotonin levels and depression, although mood-lowering effects are observed in certain vulnerable individuals.[1]
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