Английская Википедия:Adapalene/benzoyl peroxide

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Шаблон:Short description Шаблон:Infobox drug

Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of severe acne vulgaris.[1][2] It consists of a combination of adapalene and benzoyl peroxide in a topical gel formulation.[1][2]

It is available as a generic medication.[3]

Medical uses

Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris.[1][2] The topical retinoid in the gel, adapalene, normalises the development of the skin cells whilst preventing the pores from blocking and promoting the renewal of skin cells.[4]

Side effects

Commonly reported side effects include the following:[1][2]

Research

Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves.[5]

The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied;[6] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).

References

Шаблон:Reflist

External links

Шаблон:Nestlé Шаблон:Acne Agents Шаблон:Portal bar

  1. 1,0 1,1 1,2 1,3 Ошибка цитирования Неверный тег <ref>; для сносок Epiduo FDA label не указан текст
  2. 2,0 2,1 2,2 2,3 Ошибка цитирования Неверный тег <ref>; для сносок Epiduo Forte FDA label не указан текст
  3. Шаблон:Cite web
  4. Шаблон:Cite web
  5. Шаблон:Cite journal
  6. Шаблон:Cite journal