Английская Википедия:Angiomatoid fibrous histiocytoma

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Шаблон:Short description Шаблон:Infobox medical condition (new)

Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue cancer that affects children and young adults. On November 16, 2020, US MasterChef Junior participant Ben Watkins died from the disease at the age of 14.[1]

Pathology

It is characterized by cystic blood-filled spaces and composed of histiocyte-like cells. A lymphocytic cuff is common. It often simulates a vascular lesion, and was initially described as doing this.[2]

AFH typically has a chromosomal translocation involving the ATF1 gene -- t(12;16) FUS/ATF1 or t(12;22) EWS/ATF1.[3]

Diagnosis

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Treatment

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See also

References

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External links

Шаблон:Medical resources Шаблон:Oncology-stub