Английская Википедия:Anti-LKM antibody

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Версия от 15:17, 1 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} An '''anti-LKM antibody''' ('''anti–liver-kidney microsomal antibody''' or '''LKM antibody''') is any of several autoantibodies that are detected in the serum of patients with different types of acute or chronic liver disease. These antibodies are targeted against antigens of the cytochrome P450 system. ==Classificatio...»)
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An anti-LKM antibody (anti–liver-kidney microsomal antibody or LKM antibody) is any of several autoantibodies that are detected in the serum of patients with different types of acute or chronic liver disease. These antibodies are targeted against antigens of the cytochrome P450 system.

Classification

There are three kinds of anti-LKM antibodies:

Microsomal antibody Antigen Disease
anti-LKM 1 cytochrome P450 2D6 autoimmune hepatitis type II and chronic hepatitis C (10%)
anti-LKM 2 cytochrome P450 2C9 drug-induced hepatitis (tienilic acid–induced)
anti-LKM 3 cytochrome P450 1A2 chronic active hepatitis in association with autoimmune polyendocrine syndrome type 1;[1] hepatitis D

References

Шаблон:Reflist

External links

Шаблон:Immunology-stub

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  1. ↑ Gebre-Medhin G et al., FEBS Letters 1997
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