Английская Википедия:Aortic sac
Шаблон:Infobox embryology The aortic sac or aortic bulb[1] is a dilated structure in mammalian embryos, lined by endothelial cells and is the most distal part of the truncus arteriosus.[2] It is the primordial vascular channel from which the aortic arches arise (and eventually the dorsal aortae) and is homologous to the ventral aorta of gill-bearing vertebrates. The aortic sac eventually forms right and left horns, which subsequently give rise to the brachiocephalic trunk and the proximal segment of the arch of aorta, respectively.[2]
Genes HAND2 (dHAND) and HAND1 (eHAND) are expressed during the development of the aortic bulb and the arteries which arise from it.[3] The protein encoded by these genes belong to the basic helix-loop-helix family of transcription factors.
References
Шаблон:Development of circulatory system Шаблон:Authority control
- ↑ Annalisa Berta, James L. Sumich, Kit M. Kovacs. Marine Mammals: Evolutionary Biology. Academic Press, 2006; page 240.
- ↑ 2,0 2,1 Шаблон:Cite book
- ↑ Richard P. Harvey, Nadia Rosenthal (ed). Heart Development. Gulf Professional Publishing, 1999; page 150-151.
