Английская Википедия:Aristolochene synthase
Шаблон:Infobox enzyme The enzyme aristolochene synthase (EC 4.2.3.9) catalyzes the chemical reaction
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Other names in common use include sesquiterpene cyclase, trans,trans-farnesyl diphosphate aristolochene-lyase, trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing and aristolochene-forming). This enzyme participates in terpenoid biosynthesis.
This protein may use the morpheein model of allosteric regulation.[1]
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link and Шаблон:PDB link. They are both notable for the very high helix content of the structure.
References
Шаблон:Carbon-oxygen lyases Шаблон:Enzymes Шаблон:Portal bar
