Английская Википедия:Artesunate/amodiaquine

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Шаблон:Short description Шаблон:Drugbox Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria.[1][2] It is a fixed-dose combination of artesunate and amodiaquine.[1] Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria.[3] It is taken by mouth.[2]

Common side effects include loss of appetite, nausea, abdominal pain, sleepiness, trouble sleeping, and cough.[4] Safety in pregnancy is not clear; however, the medication may be used if others are not possible.[4] It is believed to be safe for use during breastfeeding.[4] Artesunate and amodiaquine are both antimalarial medication; however, work by different mechanisms.[4]

Artesunate/amodiaquine was commercially launched in 2007.[5] It is on the World Health Organization's List of Essential Medicines.[1] Artesunate/amodiaquine is available as a generic medication.[5] As of 2014 it is not commercially available in the United States or United Kingdom.[6][7]

Medical uses

Early clinical trials showed that a once-a-day dosage was effective.[8] It was subsequently clinically shown to be equally effective as artemether/lumefantrine,[9] although it is likely to be more effective in the field due to its simpler once-a-day dosage compared to artemether/lumefantrine twice-per-day dosage.

Society and culture

Artesunate/amodiaquine was commercially launched in 2007 as an affordable treatment for malaria, devised by DNDi in partnership with Sanofi-Aventis.[5] ASAQ was handed over to the MMV Access and Product Management Team in May 2015.[10]

References

Шаблон:Reflist

External links

Шаблон:Chromalveolate antiparasitics Шаблон:Portal bar

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Разное

  1. ↑ 1,0 1,1 1,2 Шаблон:Cite book
  2. ↑ 2,0 2,1 Шаблон:Cite journal
  3. ↑ Шаблон:Cite book
  4. ↑ 4,0 4,1 4,2 4,3 Шаблон:Cite web
  5. ↑ 5,0 5,1 5,2 Шаблон:Cite web
  6. ↑ Шаблон:Cite book
  7. ↑ Шаблон:Cite book
  8. ↑ Шаблон:Cite journal
  9. ↑ Шаблон:Cite journal
  10. ↑ Шаблон:Cite web
Источник — http://wikihandbk.com/ruwiki/index.php?title=Английская_Википедия:Artesunate/amodiaquine&oldid=13258919