Английская Википедия:BU72
Материал из Онлайн справочника
Шаблон:Short description Шаблон:Drugbox Шаблон:Technical
BU72 is an extremely potent opioid, with one of the highest known affinities for the μ-opioid receptor. In animal studies, it was found to be a potent analgesic, with a slow onset and long duration of action, but was not considered suitable to develop for medical use.[1] It was used to produce the first crystal structure of the active μ-opioid receptor,[2] and is now widely used to model the activation process.[3][4][5] The stereochemistry has recently been revised, with the phenyl group in the (R) configuration,[6] which has been accepted by the authors of the crystal structure.[7]
See also
References
