Английская Википедия:Bemotrizinol

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Версия от 22:41, 7 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{chembox | Verifiedfields = changed | verifiedrevid = 424200371 | ImageFile = Bemotrizinol 2D-Structural Formula V1.svg | ImageSize = 300 | PIN = 2,2′-[6-(4-Methoxyphenyl)-1,3,5-triazine-2,4-diyl]bis{5-[(2-ethylhexyl)oxy]phenol} | OtherNames = Tinosorb S<br>Bis-ethylhexyloxyphenol methoxyphenyl triazine<br>Anisotriazine |Section1={{Chembox Identifiers | Abbreviations = BEMT | UNII_R...»)
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Bemotrizinol (INN[1][2]/USAN,[3] INCI bis-ethylhexyloxyphenol methoxyphenyl triazine) is an oil-soluble organic compound that is added to sunscreens to absorb UV rays. It is marketed as Parsol Shield, Tinosorb S, and Escalol S.

Bemotrizinol is a broad-spectrum UV absorber, absorbing UVB as well as UVA rays. It has two absorption peaks, 310 and 340 nm.[4] It is highly photostable. Even after 50 MEDs (minimal erythemal doses), 98.4% remains intact. It helps prevent the photodegradation of other sunscreen actives like avobenzone.[5] A recent development is Tinosorb S Aqua, which is bemotrizinol in a PMMA matrix dispersed in water. This makes it possible to add bemotrizinol to the water phase.[6]

Bemotrizinol has strong synergistic effects on the SPF when formulated with bisoctrizole, ethylhexyl triazone or iscotrizinol.[7] It is the most effective UV absorber available measured by SPF, based on the maximum concentration permitted by European legislation.[8]

As of 2022,[9] bemotrizinol is not approved by the United States Food and Drug Administration for use in sunscreens, but has been approved in the European Union since 2000[10] and some other parts of the world, including Australia.[11][12]

Unlike some other organic sunscreen actives, it shows no estrogenic effects in vitro.[13]

References

Шаблон:Reflist

Шаблон:Sunscreening agents