Английская Википедия:Bimekizumab
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Bimekizumab, sold under the brand name Bimzelx, is a humanized anti-IL17A, anti-IL-17F, and anti-IL17AF monoclonal antibody[1][2] that is used to treat plaque psoriasis, psoriatic arthritis, axial spondyloarthritis, and ankylosing spondylitis.[1]
The most common side effects include upper respiratory tract infections (nose and throat infection) and oral candidiasis (thrush, a fungal infection in the mouth or throat).[1] Injection site reactions were also common, reported in 3% of subjects.[3]
Bimekizumab was approved for medical use in the European Union in August 2021,[1][4][5] and in the United States in October 2023.[6][7]
Medical uses
In the EU, bimekizumab is indicated for the treatment of moderate to severe plaque psoriasis, active psoriatic arthritis, non-radiographic axial spondyloarthritis, and active ankylosing spondylitis.[1]
History
Bimekizumab is being developed by Belgian pharmaceutical company UCB.Шаблон:Citation needed
Society and culture
Names
Bimekizumab is the international nonproprietary name (INN).[8]
Research
Phase III trials have demonstrated that bimekizumab is superior to not only adalimumab[9] but also secukinumab[10] and ustekinumab[11] for the treatment of plaque psoriasis.
References
Further reading
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