Английская Википедия:Bomanin
Шаблон:Infobox nonhuman protein
The Bomanin gene family encodes a group of immune peptides that are essential for Drosophila fruit fly defence against infection by many pathogens.[1][2]
The gene family is named in honour of Hans G. Boman, for his contributions to innate immunity and the discovery of antimicrobial peptides.[1] While Bomanins are essential for survival after infection by many kinds of Gram-positive bacteria and pathogenic fungi, the reason they are key to defence may be because Bomanins promote resilience to pathogen toxins, and not because they directly suppress pathogens.[3] However fly hemolymph (blood) loses its fungicidal activity in the absence of Bomanins, suggesting these peptides are also somehow needed to turn the hemolymph into an antimicrobial environment.[4]
See also
- Hans G. Boman
- Antimicrobial peptides
- Drosomycin
- Metchnikowin
- Baramicin
- Daisho
- The Toll immunity signalling pathway
References
