Английская Википедия:C3a receptor

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Версия от 08:15, 13 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in humans}} {{Infobox_gene}} The '''C3a receptor''' also known as '''complement component 3a receptor 1''' ('''C3AR1''') is a G protein-coupled receptor protein involved in the complement system.<ref name="pmid8605247">{{cite journal | vauthors = Roglic A, Prossnitz ER, Cavanagh SL, Pan Z, Zou A, Ye RD | title = cDNA cloning of a novel G...»)
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Шаблон:Short description Шаблон:Infobox gene

The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein-coupled receptor protein involved in the complement system.[1][2]

The receptor binds to complement component C3a, although there is limited evidence that this receptor also binds C4a in lesser mammals. This has yet to be proven true in humans.[3] C3a receptor modulates immunity,[4] arthritis, diet-induced obesity[5] and cancers.[6]

Agonists and antagonists

Potent and selective agonists[7] and antagonists[8] for C3aR have been discovered.

References

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Further reading

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External links

Шаблон:Complement system Шаблон:G protein-coupled receptors Шаблон:Gene-12-stub