Английская Википедия:CEP350
Шаблон:Short description Шаблон:Infobox gene Centrosome-associated protein 350 is a protein that in humans is encoded by the CEP350 gene.[1][2][3]
CEP350 is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. It primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. CEP350 is required to anchor microtubules at the centrosome. Furthermore, it increases the stability of growing centrioles.[4]
It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined.[3]
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Шаблон:Refend Шаблон:PDB Gallery Шаблон:Centrosome