Английская Википедия:CEP350

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Версия от 10:58, 13 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} '''Centrosome-associated protein 350''' is a protein that in humans is encoded by the ''CEP350'' gene.<ref name="pmid16314388">{{cite journal | vauthors = Yan X, Habedanck R, Nigg EA | title = A Complex of Two Centrosomal Proteins, CAP350 and FOP, Cooperates with EB1 in Microtubule Anchoring...»)
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Шаблон:Short description Шаблон:Infobox gene Centrosome-associated protein 350 is a protein that in humans is encoded by the CEP350 gene.[1][2][3]

CEP350 is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. It primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. CEP350 is required to anchor microtubules at the centrosome. Furthermore, it increases the stability of growing centrioles.[4]

It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined.[3]

References

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Further reading

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Шаблон:Refend Шаблон:PDB Gallery Шаблон:Centrosome


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