Английская Википедия:CEP63
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Шаблон:Short description Шаблон:Infobox gene Centrosomal protein of 63 kDa is a protein that in humans is encoded by the CEP63 gene.[1][2] Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Function
This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.[2] Recent computational analysis revealed pathogenic property of L61P point mutation in CEP63 protein that affected its native structural conformation.[3]
Interactions
CEP63 has been shown to interact with DISC1,[4] CEP152 and CDK1.[3]
References
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Further reading
