Английская Википедия:CYP3A

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Версия от 18:45, 13 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Human gene}} {{Infobox_gene}} '''Cytochrome P450, family 3, subfamily A''', also known as '''CYP3A''', is a human gene locus.<ref name="entrez">{{cite web | title = Entrez Gene: CYP3A cytochrome P450, family 3, subfamily A| url = https://www.ncbi.nlm.nih.gov/gene/1574}}</ref><ref name="pmid11266076">{{cite journal | vauthors = Gellner K, Eiselt R, Hustert E, Arn...»)
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Шаблон:Short description Шаблон:Infobox gene Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene locus.[1][2] A homologous locus is found in mice.[3]

The CYP3A locus includes all the known members of the 3A subfamily of the cytochrome P450 superfamily of genes. These genes encode monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP3A cluster consists of four genes:

The region also contains four pseudogenes:

as well as several extra exons which may or may not be included in transcripts produced from this region. Previously another CYP3A member, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4.[1]

References

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Further reading

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Шаблон:Cytochrome P450 Шаблон:Dioxygenases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:Protein-stub

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  1. ↑ 1,0 1,1 Шаблон:Cite web
  2. ↑ Шаблон:Cite journal
  3. ↑ Шаблон:Cite journal
Источник — http://wikihandbk.com/ruwiki/index.php?title=Английская_Википедия:CYP3A&oldid=13718158