Английская Википедия:CYP3A43

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Версия от 18:45, 13 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in the species Homo sapiens}} {{cs1 config|name-list-style=vanc}} {{Infobox_gene}} '''Cytochrome P450 3A43''' is a protein that in humans is encoded by the ''CYP3A43'' gene.<ref name="pmid11160876">{{cite journal | vauthors = Domanski TL, Finta C, Halpert JR, Zaphiropoulos PG | title = cDNA cloning and initial characterization of CYP3A43,...»)
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Шаблон:Short description Шаблон:Cs1 config Шаблон:Infobox gene Cytochrome P450 3A43 is a protein that in humans is encoded by the CYP3A43 gene.[1][2][3]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.[3]

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Шаблон:Refend Шаблон:Cytochrome P450


Шаблон:Gene-7-stub