Английская Википедия:Catabasis Pharmaceuticals

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Версия от 17:43, 15 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{multiple issues|{{citation style|date=August 2013}} {{one source|date=November 2019}}}} {{Infobox company | name = Catabasis Pharmaceuticals | logo = Catabasis_Logo.png | type = Public | traded_as = {{NASDAQ|CATB}}<br />Russell Microcap Index component | industry = Pharmaceuticals | founded = {{start date and age|2008}} | location = Cambridge, Massachuset...»)
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Catabasis Pharmaceuticals, founded in 2008 and based in Cambridge, Massachusetts, is a clinical-stage biopharmaceutical company.[1] Their lead program is edasalonexent, an NF-kB inhibitor in development for the treatment of Duchenne muscular dystrophy.

In Catabasis’s Phase 2 MoveDMD clinical trial and open-label extension, edasalonexent was shown to preserve muscle function as assessed by the North Star Ambulatory Assessment and Timed Function Tests compared with the rate of change during an off-treatment control period. It also showed a significant decrease in CRP, muscle enzymes including CK, and decrease in heart rate to age-normative values.

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