Английская Википедия:Chloroprednisone
Шаблон:Short description Шаблон:Drugbox
Chloroprednisone is a topical glucocorticoid first reported in 1960.[1] It is a chlorinated derivative of prednisone. The acetate ester prodrug, chloroprednisone 21-acetate, was sold under the brand name Topilan as an anti-inflammatory agent.[2][3]
There is little published about chloroprednisone. This may be due to limited activity topically because the skin lacks the necessary activating enzyme 11-Beta hydroxysteroid dehydrogenase. Systemically, this agent's activity on glucocorticoid receptors may not have competed with agents like fludrocortisone or dexamethasone.
References
Шаблон:Glucocorticoids
Шаблон:Glucocorticoidics
Шаблон:Systemic-hormonal-drug-stub
