Английская Википедия:Collagen, type V, alpha 2

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Версия от 07:14, 20 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein found in humans}} {{Infobox_gene}} '''Collagen alpha-2(V) chain''' is a protein that in humans is encoded by the ''COL5A2'' gene.<ref name="pmid1572660">{{cite journal | vauthors = Greenspan DS, Byers MG, Eddy RL, Cheng W, Jani-Sait S, Shows TB | title = Human collagen gene COL5A1 maps to the q34.2----q34.3 region of chromosome 9, near the locus for...»)
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Шаблон:Short description Шаблон:Infobox gene Collagen alpha-2(V) chain is a protein that in humans is encoded by the COL5A2 gene.[1][2]

This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, classical type, formerly known as types I and II.[2]

See also

References

Шаблон:Reflist

Further reading

Шаблон:Refbegin

Шаблон:Refend

External links

Шаблон:Fibrous proteins

Шаблон:Gene-2-stub

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  1. ↑ Шаблон:Cite journal
  2. ↑ 2,0 2,1 Шаблон:Cite web
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