Английская Википедия:DEFB103A

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Версия от 20:20, 23 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in humans}} {{Infobox_gene}} '''Beta-defensin 103''' is a protein that in humans is encoded by the ''DEFB103A'' gene.<ref name="pmid11223260">{{cite journal | vauthors = Jia HP, Schutte BC, Schudy A, Linzmeier R, Guthmiller JM, Johnson GK, Tack BF, Mitros JP, Rosenthal A, Ganz T, ((McCray PB Jr)) | title = Discovery of new human beta-defe...»)
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Шаблон:Short description Шаблон:Infobox gene Beta-defensin 103 is a protein that in humans is encoded by the DEFB103A gene.[1][2][3]

Function

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.[3]

In dogs, the product of the same genetic locus, β-Defensin 103, also plays a role in pigmentation, being an agonist of the melanocortin 1 receptor.[4]

References

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Further reading

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