Английская Википедия:DEFB105A

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Версия от 20:20, 23 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in humans}} {{Infobox_gene}} '''Beta-defensin 105''' is a protein that is encoded by the ''DEFB105A'' gene in humans.<ref name="pmid11854508">{{cite journal | vauthors = Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, ((McCray PB Jr)) | title = Discovery of five conserved beta -defensin gene clusters using a...»)
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Шаблон:Short description Шаблон:Infobox gene Beta-defensin 105 is a protein that is encoded by the DEFB105A gene in humans.[1][2][3]

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: Alpha defensins, Beta defensins and Theta defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy.[3]

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