Английская Википедия:Dasolampanel
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Dasolampanel (INN, USAN, code name NGX-426) is an orally bioavailable analog of tezampanel and thereby competitive antagonist of the AMPA and kainate receptors which was under development by Raptor Pharmaceuticals/Torrey Pines Therapeutics for the treatment of chronic pain conditions including neuropathic pain and migraine.[1] It was developed as a follow-on compound to tezampanel, as tezampanel is not bioavailable orally and must be administered by intravenous injection,[2][3] but ultimately neither drug was ever marketed.
See also
References
Шаблон:Antimigraine preparations Шаблон:Neuropathic pain pharmacotherapies Шаблон:Ionotropic glutamate receptor modulators
- Английская Википедия
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- Decahydroisoquinolines
- Kainate receptor antagonists
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- Tetrazoles
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