Английская Википедия:Dasolampanel

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Версия от 22:45, 24 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Chemical compound}} {{Drugbox | IUPAC_name = (3''S'',4a''S'',6''S'',8a''R'')-6-(3-Chloro-2-(1''H''-tetrazol-5-yl)phenoxy)decahydroisoquinoline-3-carboxylic acid | image = Dasolampanel.svg | CAS_number = 503294-13-1 | ATC_prefix = None | ATC_suffix = | PubChem = 51049972 | DrugBank = | ChemSpiderID =...»)
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Dasolampanel (INN, USAN, code name NGX-426) is an orally bioavailable analog of tezampanel and thereby competitive antagonist of the AMPA and kainate receptors which was under development by Raptor Pharmaceuticals/Torrey Pines Therapeutics for the treatment of chronic pain conditions including neuropathic pain and migraine.[1] It was developed as a follow-on compound to tezampanel, as tezampanel is not bioavailable orally and must be administered by intravenous injection,[2][3] but ultimately neither drug was ever marketed.

See also

References

Шаблон:Reflist

Шаблон:Antimigraine preparations Шаблон:Neuropathic pain pharmacotherapies Шаблон:Ionotropic glutamate receptor modulators


Шаблон:Analgesic-stub