Английская Википедия:Demexiptiline
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Demexiptiline (brand names Deparon, Tinoran) is a tricyclic antidepressant (TCA) used in France for the treatment of depression.[1][2] It acts primarily as a norepinephrine reuptake inhibitor similarly to desipramine.[3]
Synthesis
The synthesis is similar to that reported for Noxiptiline but also differs in a couple of respects.
The condensation between Dibenzosuberenone [2222-33-5] (1) and hydroxylamine (2) gives the oxime, [1021-91-6] (3). Base catalyzed attachment of the sidechain by reaction with 2-Chloro-N-Methylethanamine [32315-92-7] (4) completed the synthesis of demexiptiline (5).
References
Further reading
Шаблон:Antidepressants Шаблон:Navboxes Шаблон:Tricyclics Шаблон:Use dmy dates
Шаблон:Nervous-system-drug-stub
