Английская Википедия:Diaminopimelate dehydrogenase
Шаблон:Infobox enzyme In enzymology, a diaminopimelate dehydrogenase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction
- meso-2,6-diaminoheptanedioate + H2O + NADP+ <math>\rightleftharpoons</math> L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+
The 3 substrates of this enzyme are meso-2,6-diaminoheptanedioate, H2O, and NADP+, whereas its 4 products are L-2-amino-6-oxoheptanedioate, NH3, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating). Other names in common use include meso-alpha,epsilon-diaminopimelate dehydrogenase, and meso-diaminopimelate dehydrogenase. This enzyme participates in lysine biosynthesis.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.
References
Шаблон:CH-NH2 oxidoreductases Шаблон:Enzymes Шаблон:Portal bar
