Английская Википедия:Dihydrotestosterone undecanoate

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Версия от 10:41, 27 февраля 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Chemical compound}} {{Drugbox | Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [(5''S'',8''R'',9''S'',10''S'',13''S'',14''S'',17''S'')-10,13-Dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[''a'']phenanthren-17-yl] undecanoate | image = Dihydrotestosterone undecanoate.svg | width = 250px <!--Clinical data--> | traden...»)
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Dihydrotestosterone undecanoate (DHTU), also known as androstanolone undecanoate or stanolone undecanoate, is a synthetic androgen and anabolic steroid (AAS) which was never marketed.[1][2][3][4] It is an androgen ester; specifically, it is the C17β undecanoate (undecylate) ester of dihydrotestosterone (DHT).[1][2][3][4][5] DHTU is a prodrug of DHT.[1][5][4] Similarly to testosterone undecanoate (TU), DHTU is orally active.[2][3][4] It occurs as an important active metabolite of oral TU.[6][1][5][7][8] The 5α-reductase inhibitor finasteride in combination with oral TU has no effect on the first-pass transformation of TU into DHTU or DHT, probably because of its unique lymphatic route of absorption.[9] Oral DHTU may be absorbed by the lymphatic system similarly to TU, and this may explain its oral bioavailability.[1][2][3][4]

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Шаблон:Androgen receptor modulators