Английская Википедия:EF-24

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Версия от 07:05, 1 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Chemical compound}} {{Drugbox | IUPAC_name = (3E,5E)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one | image = EF-24 Structure.svg <!--Clinical data--> | tradename = | legal_US = | legal_status = <!--Pharmacokinetic data--> | bioavailability = | metabolism = | elimination_half-life = | excretion = <!--Identifiers--> | CAS_number = 342808-40-6 | PubChem...»)
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EF-24 is a compound that is a synthetic analogue of curcumin, a bioactive phytochemical from turmeric. Curcumin has antioxidant, antibiotic, anti-inflammatory and anti-cancer properties in vitro but has low potency and very poor bioavailability when taken orally, resulting in limited efficacy. EF-24 was developed to try to improve upon these properties, and has been found to be around 10x more potent than curcumin and with much higher systemic bioavailability. It has never been developed for medical use, though research continues to investigate whether it may be useful as an adjuvant treatment for some cancers alongside conventional chemotherapy drugs.[1][2][3][4][5]

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