Английская Википедия:Efavirenz/lamivudine/tenofovir
Шаблон:Short description Шаблон:Infobox drug
Efavirenz/lamivudine/tenofovir (EFV/3TC/TDF), sold under the brand name Symfi among others, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS.[1][2][3] It combines efavirenz, lamivudine, and tenofovir disoproxil.[3] Шаблон:As of, it is listed by the World Health Organization as an alternative first line option to dolutegravir/lamivudine/tenofovir.[4] It is taken by mouth.[1][2][3]
Side effects can include joint pain, sleepiness, headaches, depression, trouble sleeping, and itchiness.[3] Severe side effects may include depression, psychosis, or osteonecrosis.[3] In those with a history of epilepsy, it may increase the frequency of seizures.[3] Greater care should also be taken in those with kidney problems.[3] Its use during pregnancy appears to be unsafe.[1][2]
It is on the World Health Organization's List of Essential Medicines.[5] The combination received tentative approval in the United States in 2014,[6] and was granted approval in February 2018.[7][8] Its availability and importance is supported by Medecins Sans Frontieres.[3] It is available as a generic medication.[9][10][11]
References
External links
Шаблон:HIVpharm Шаблон:Portal bar
Шаблон:Antiinfective-drug-stub
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; для сносокSymfi FDA label
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; для сносокSymfi Lo FDA label
не указан текст - ↑ 3,0 3,1 3,2 3,3 3,4 3,5 3,6 3,7 Шаблон:Cite web
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- ↑ Шаблон:Cite web
- ↑ Шаблон:Cite web
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