Английская Википедия:Epimerase and racemase

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Версия от 02:31, 4 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} '''Epimerases''' and '''racemases''' are isomerase enzymes that catalyze the inversion of stereochemistry in biological molecules.<ref>{{cite journal | author = Tanner, ME. | title = Understanding nature's strategies for enzyme-catalyzed racemization and epimerization | journal = Acc. Chem. Res. | year=2002 | volume=35 | issue=4 | pages=237–246 | pmid = 11955052 | doi = 1...»)
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Epimerases and racemases are isomerase enzymes that catalyze the inversion of stereochemistry in biological molecules.[1] Racemases catalyze the stereochemical inversion around the asymmetric carbon atom in a substrate having only one center of asymmetry. Epimerases catalyze the stereochemical inversion of the configuration about an asymmetric carbon atom in a substrate having more than one center of asymmetry, thus interconverting epimers.

Human epimerases include methylmalonyl-CoA epimerase, involved in the metabolic breakdown of the amino acids alanine, isoleucine, methionine and valine,[2] and UDP-glucose 4-epimerase, which is used in the final step of galactose metabolism - catalyzing the reversible conversion of UDP-galactose to UDP-glucose.

See also

References

Шаблон:Reflist

External links

Шаблон:Racemases and epimerases


Шаблон:Enzyme-stub

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  1. ↑ Шаблон:Cite journal
  2. ↑ Шаблон:Cite web
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