Английская Википедия:Estradiol benzoate/estradiol phenylpropionate
Шаблон:Short description Шаблон:Drugbox
Estradiol benzoate/estradiol phenylpropionate (EB/EPP), sold under the brand name Dimenformon Prolongatum, is an injectable combination formulation of estradiol benzoate (EB), a shorter-acting estrogen, and estradiol phenylpropionate (EPP), a longer-acting estrogen, which has been used in menopausal hormone therapy for women in Europe but appears to no longer be available.[1][2][3][4] It has also been used to suppress lactation in women and has been used in feminizing hormone therapy for transgender women.[5][6] It has been provided in the form of 1 mL ampoules containing 2.5 mg EB and 10 mg EPP in oil solution and is administered by intramuscular injection at regular intervals.[2]
The pharmacokinetics of this formulation and its constituent components have been studied.[7][8][9][10][11][12]
A combination of 12.5 mg EB and 10 mg EPP (developmental code name Org 369–2) has been studied for use in women as a postcoital contraceptive within 48 hours of unprotected sex.[13][9][14][15][16]
See also
- Estradiol/estradiol enanthate
- Estradiol benzoate/estradiol phenylpropionate/testosterone propionate/testosterone phenylpropionate/testosterone isocaproate
- Estradiol benzoate/estradiol valerate/hydroxyprogesterone caproate
- List of combined sex-hormonal preparations
References
Шаблон:Estrogens and antiestrogens Шаблон:Estrogen receptor modulators Шаблон:Genito-urinary-drug-stub
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- ↑ 9,0 9,1 Шаблон:Cite journal
- ↑ Шаблон:Cite journal
- ↑ Шаблон:Cite book
- ↑ Шаблон:Cite journal
- ↑ Шаблон:Cite book
- ↑ Шаблон:Cite journal
- ↑ Шаблон:Cite book
- ↑ Шаблон:Cite journal