Английская Википедия:Estriol dihexanoate

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Версия от 19:33, 4 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Chemical compound}} {{Drugbox | Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [(8''R'',9''S'',13''S'',14''S'',16''R'',17''R'')-3-hexanoyloxy-16-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[''a'']phenanthren-17-yl] hexanoate | image = Estriol 3,17-dihexanoate.svg | width = 250px <!--Clinical data--> | tradename = | pregn...»)
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Estriol dihexanoate, or estriol 3,17β-dihexanoate, is a synthetic estrogen and estrogen ester – specifically, the C3 and C17β dihexanoate ester of estriol – which was first described in 1963 and was never marketed.[1][2][3] Following a single intramuscular injection of 8.90 mg estriol dihexanoate (equivalent to 5.0 mg estriol) in an oil solution, peak levels of estriol occurred after 2.1 to 3.4 days, an elimination half-life of 187 to 221 hours was observed, and estriol levels remained elevated for up to 20 to 50 days.[1][3] For comparison, the durations of estriol and estriol dipropionate were far shorter.[1][3]

See also

References

Шаблон:Reflist

Шаблон:Estrogen receptor modulators

Шаблон:Steroid-stub Шаблон:Genito-urinary-drug-stub