Английская Википедия:Etynodiol
Шаблон:Short description Шаблон:Drugbox
Etynodiol, or ethynodiol, is a steroidal progestin of the 19-nortestosterone group which was never marketed.[1][2][3] A diacylated derivative, etynodiol diacetate, is used as a hormonal contraceptive.[1][2] Etynodiol is sometimes used as a synonym for etynodiol diacetate.
It was patented in 1955.[4]
Pharmacology
Etynodiol is a prodrug of norethisterone, and is converted immediately and completely into norethisterone.[5][6][7] Etynodiol is an intermediate in the conversion of the prodrug lynestrenol into norethisterone.[8]
Шаблон:Relative affinities of norethisterone, metabolites, and prodrugs
Chemistry
Etynodiol is a 19-nortestosterone derivative. Structurally, it is almost identical to norethisterone and lynestrenol, differing only in its C3 substituent. Whereas norethisterone has a ketone at C3 and lynestrenol has no substituent at C3, etynodiol has a hydroxyl group at the position.
Synthesis
Society and culture
Generic names
Etynodiol is the generic name of the drug and its Шаблон:Abbrlink, while ethynodiol is its Шаблон:Abbrlink.[1][2]
References
Шаблон:Progesterone receptor modulators Шаблон:Estrogen receptor modulators Шаблон:Androgen receptor modulators
Шаблон:Steroid-stub Шаблон:Genito-urinary-drug-stub
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