Английская Википедия:F2RL2

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Версия от 22:30, 5 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{cs1 config|name-list-style=vanc}} {{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} '''Protease activated receptor 3''' ('''PAR-3''') also known as '''coagulation factor II receptor-like 2''' (F2RL2) and '''thrombin receptor-like 2''', is a protein that in humans is encoded by the '''F2RL2''' gene. == Function == Coagulation factor II (t...»)
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Шаблон:Cs1 config Шаблон:Short description Шаблон:Infobox gene Protease activated receptor 3 (PAR-3) also known as coagulation factor II receptor-like 2 (F2RL2) and thrombin receptor-like 2, is a protein that in humans is encoded by the F2RL2 gene.

Function

Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane receptors that couple to G proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.[1]

See also

References

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Further reading

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Шаблон:NLM content Шаблон:G protein-coupled receptors Шаблон:Transmembranereceptor-stub

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  1. ↑ Шаблон:Cite web
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