Английская Википедия:Fcab

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Шаблон:Short description Шаблон:About

Fcabs are antibodies fragments engineered from the constant region of an antibody (Fc).[1] In naturally occurring antibodies (such as IgGs), the antigen-binding sites are located at the variable regions (Fab).

Overview

Fcabs can be expressed as soluble proteins or they can be engineered back into a full IgG. This type of antibodies are therefore able to recognise two different antigens, one at their Fab region and a second one at the Fc region, hence the name of bispecific antibodies. This antibody fragment is part of the modular antibody technology of F-star Biotechnology Ltd.Шаблон:Cn

See also

References

Шаблон:Reflist