Английская Википедия:Frizzled-6
Материал из Онлайн справочника
Шаблон:Short description Шаблон:Infobox gene Frizzled-6 (Fz-6) is a protein that in humans is encoded by the FZD6 gene.[1][2][3]
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for WNT signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other FZD family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif.[3] Fz-6 is believed to be the receptor for the WNT4 ligand.[4]
Interactions
Fz-6 has been shown to interact with secreted frizzled-related protein 1.[5]
References
Further reading
- Шаблон:Cite journal
- Шаблон:Cite journal
- Шаблон:Cite journal
- Шаблон:Cite journal
- Шаблон:Cite journal
- Шаблон:Cite journal
External links
Шаблон:NLM content Шаблон:G protein-coupled receptors