Английская Википедия:Frizzled-6

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Версия от 09:26, 10 марта 2024; EducationBot (обсуждение | вклад) (Новая страница: «{{Английская Википедия/Панель перехода}} {{Short description|Protein-coding gene in the species Homo sapiens}} {{Infobox_gene}} '''Frizzled-6''' '''(Fz-6)''' is a protein that in humans is encoded by the ''FZD6'' gene.<ref name="pmid9480858">{{cite journal | vauthors = Tokuhara M, Hirai M, Atomi Y, Terada M, Katoh M | title = Molecular cloning of human Frizzled-6 | journal = Biochemical and Biophysical Research Commun...»)
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Шаблон:Short description Шаблон:Infobox gene Frizzled-6 (Fz-6) is a protein that in humans is encoded by the FZD6 gene.[1][2][3]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for WNT signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other FZD family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif.[3] Fz-6 is believed to be the receptor for the WNT4 ligand.[4]

Interactions

Fz-6 has been shown to interact with secreted frizzled-related protein 1.[5]

References

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Further reading

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External links

Шаблон:NLM content Шаблон:G protein-coupled receptors